
产品货号:
Z15159
中文名称:
E2F6抗体
英文名称:
Anti-E2F6 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-E2F6 Antibody |
指标别名 | E2F transcription factor 6;E2F-6;E2F6;EMA |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB |
基因名称 | E2F6 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthetic peptide corresponding to a sequence in the middle region of human E2F6(162-177aa KDCAQQLFELTDDKEN),different from the related mouse and rat sequences by one amino acid. |
实际分子量 | 32KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | E2F6(E2F transcription factor 6) also known as E2F-6.Northern blot analysis revealed that E2F6 is expressed as 2 mRNAs,2.5 and 3.5kb,in all human tissues and cell lines tested.The predicted human and mouse E2F6 protein sequences are 92% identical.The DNA-binding and dimerization domains of E2F6 are highly related to those of other E2F family members,but this protein lacks the sequences necessary for either transcriptional activation or binding to RB1,p107,or p130.E2F6°Can act to repress the transcription of E2F-responsive genes by countering the activity of other E2F complexes.E2F6°Contributes to gene silencing in a manner independent of retinoblastoma protein family members.E2F6 is found in a multimeric protein complex that contains MGA and MAX,and thus the complex can bind not only to the E2F binding site but also to MYC- and Brachyury- binding sites.The E2F6°Complex preferentially occupies target promoters in G0 cells rather than in G1 cells. |
Uniprot ID | O75461 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
基因名全称 | E2F transcription factor 6 |
蛋白名全称 | Transcription factor E2F6(E2F-6) |
推荐稀释比 | Western blot(WB) 1:500~2000 |
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